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1

Adjuvants and the promotion of Th1-type cytokines in tumour immunotherapy

Keith Dredge, Blake J. Marriott, Stephen M. Todryk, Angus G. Dalgleish

Journal:

Cancer Immunology, Immunotherapy

Year:

2002

Language:

english

File:

PDF, 357 KB

english, 2002

2

Safety, Immunogenicity, and Efficacy of Prime-Boost Immunization with Recombinant Poxvirus FP9 and Modified Vaccinia Virus Ankara Encoding the Full-Length Plasmodium falciparum Circumsporozoite Protein

Walther, M., Thompson, F. M., Dunachie, S., Keating, S., Todryk, S., Berthoud, T., Andrews, L., Andersen, R. F., Moore, A., Gilbert, S. C., Poulton, I., Dubovsky, F., Tierney, E., Correa, S., Huntcook

Journal:

Infection and Immunity

Year:

2006

Language:

english

File:

PDF, 247 KB

english, 2006

3

Experimental mucosal induction of uveitis with the 60-kDa heat shock protein-derived peptide 336 – 351

Wei Hu, Adam Hasan, Amanda Wilson, Miles Richard Stanford, Yun Li-Yang, Steven Todryk, Roy Whiston, Thomas Shinnick, Yutaka Mizushima, Ruurd Van der Zee, Thomas Lehner

Journal:

European Journal of Immunology

Year:

1998

Language:

english

File:

PDF, 204 KB

english, 1998

4

Depletion of NK cells results in disseminating lethal infection with Bordetella pertussis associated with a reduction of antigen-specific Th1 and enhancement of Th2, but not Tr1 cells

Patricia Byrne, Peter McGuirk, Stephen Todryk, Kingston H. G. Mills

Journal:

European Journal of Immunology

Year:

2004

Language:

english

File:

PDF, 238 KB

english, 2004

5

Multiple functions of human T cells generated by experimental malaria challenge

Stephen M. Todryk, Michael Walther, Philip Bejon, Claire Hutchings, Fiona M. Thompson, Britta C. Urban, David W. Porter, Adrian V. S. Hill

Journal:

European Journal of Immunology

Year:

2009

Language:

english

File:

PDF, 346 KB

english, 2009

6

Malaria vaccine development: Lessons from the field

Stephen Todryk, Philip Bejon

Journal:

European Journal of Immunology

Year:

2009

Language:

english

File:

PDF, 377 KB

english, 2009

7

Correction: Malaria vaccine development: Lessons from the field

Stephen Todryk, Philip Bejon

Journal:

European Journal of Immunology

Year:

2011

File:

PDF, 37 KB

2011

8

Correction: Multiple functions of human T cells generated by experimental malaria challenge

Stephen M. Todryk, Michael Walther, Philip Bejon, Claire Hutchings, Fiona M. Thompson, Britta C. Urban, David W. Porter, Adrian V. S. Hill

Journal:

European Journal of Immunology

Year:

2011

File:

PDF, 37 KB

2011

9

Heat shock proteins refine the danger theory

S. M. Todryk, A. A. Melcher, A. G. Dalgleish, R. G. Vile

Journal:

Year:

2000

Language:

english

File:

PDF, 128 KB

english, 2000

10

Efficacy of cytokine gene transfection may differ for autologous and allogeneic tumour cell vaccines

S. M. Todryk, L. J. Birchall, R. Erlich, N. Halanek, J. K. Orleans-Lindsay, A. G. Dalgleish

Journal:

Year:

2001

Language:

english

File:

PDF, 278 KB

english, 2001

11

A sense of tumour for the immune system

Journal:

Year:

2002

Language:

english

File:

PDF, 49 KB

english, 2002

12

Facets of heat shock protein 70 show immunotherapeutic potential

Stephen M. Todryk, Michael J. Gough, A. Graham Pockley

Journal:

Year:

2003

Language:

english

File:

PDF, 158 KB

english, 2003

13

Heat shock protein derived from a non-autologous tumour can be used as an anti-tumour vaccine

David G. Casey, Joanne Lysaght, Tharappel James, Andrew Bateman, Alan A. Melcher, Stephen M. Todryk

Journal:

Year:

2003

Language:

english

File:

PDF, 113 KB

english, 2003

14

A novel method to identify and characterise peptide mimotopes of heat shock protein 70-associated antigens

Blanca Arnaiz, Laura Madrigal-Estebas, Stephen Todryk, Tharappel C James, Derek G Doherty, Ursula Bond

Journal:

Journal of Immune Based Therapies and Vaccines

Year:

2006

Language:

english

File:

PDF, 1.01 MB

english, 2006

15

Efficient delivery of small interfering RNA for inhibition of IL-12p40 expressionin vivo

Marion A Flynn, David G Casey, Stephen M Todryk, Bernard P Mahon

Journal:

Journal of Inflammation

Year:

2004

Language:

english

File:

PDF, 1.65 MB

english, 2004

16

Malaria pigment paralyzes dendritic cells

Britta C Urban, Stephen Todryk

Journal:

Journal of Biology

Year:

2006

Language:

english

File:

PDF, 246 KB

english, 2006

17

Apoptosis or necrosis for tumor immunotherapy: what's in a name?

Alan Melcher, Michael Gough, Stephen Todryk, Richard Vile

Journal:

Journal of Molecular Medicine

Year:

1999

Language:

english

File:

PDF, 158 KB

english, 1999

18

Immunotherapeutic potential of whole tumour cells

Stephen Ward, David Casey, Marie-Christine Labarthe, Michael Whelan, Angus Dalgleish, Hardev Pandha, Stephen Todryk

Journal:

Cancer Immunology, Immunotherapy

Year:

2002

Language:

english

File:

PDF, 156 KB

english, 2002

19

Heated tumour cells of autologous and allogeneic origin elicit anti-tumour immunity

StephenM. Todryk, Jonathan Eaton, Lindsay Birchall, Rebecca Greenhalgh, Diane Soars, AngusG. Dalgleish, AlanA. Melcher, HardevS. Pandha

Journal:

Cancer Immunology, Immunotherapy

Year:

2004

Language:

english

File:

PDF, 320 KB

english, 2004

20

Nitroreductase-based therapy of prostate cancer, enhanced by raising expression of heat shock protein 70, acts through increased anti-tumour immunity

Kai S. Lipinski, Steven Pelech, Andrew Mountain, Alistair S. Irvine, Robert Kraaij, Chris H. Bangma, Kingston H. G. Mills, Stephen M. Todryk

Journal:

Cancer Immunology, Immunotherapy

Year:

2006

Language:

english

File:

PDF, 438 KB

english, 2006

21

The biological effects of syngeneic and allogeneic cytokine-expressing prophylactic whole cell vaccines and the influence of irradiation in a murine melanoma model

Marie-Christine Labarthe, Nicole Halanek, Lindsay Birchall, Nick Russell, Christiane Desel, Stephen Todryk, Marcus J. Peters, Aisha Lucas, Frank W. Falkenberg, Angus G. Dalgleish, Mike Whelan, Stephen

Journal:

Cancer Immunology, Immunotherapy

Year:

2006

Language:

english

File:

PDF, 614 KB

english, 2006

22

A novel murine model of allogeneic vaccination against prostate cancer

M.-C. Labarthe, P. Theocharous, N. Russell, S. Todryk, C. Bangma, P. Thraves, A. G. Dalgleish, M. A. Whelan

Journal:

Cancer Immunology, Immunotherapy

Year:

2008

Language:

english

File:

PDF, 390 KB

english, 2008

23

A prostate cancer vaccine comprising whole cells secreting IL-7, effective against subcutaneous challenge, requires local GM-CSF for intra-prostatic efficacy

Caroline Schroten-Loef, Corrina M. A. de Ridder, Suzanne Reneman, Marije Crezee, Angus Dalgleish, Stephen M. Todryk, Chris H. Bangma, Robert Kraaij

Journal:

Cancer Immunology, Immunotherapy

Year:

2009

Language:

english

File:

PDF, 530 KB

english, 2009

24

The anti-cancer agents lenalidomide and pomalidomide inhibit the proliferation and function of T regulatory cells

Christine Galustian, Brendan Meyer, Marie-Christine Labarthe, Keith Dredge, Deborah Klaschka, Jake Henry, Stephen Todryk, Roger Chen, George Muller, David Stirling, Peter Schafer, J. Blake Bartlett, A

Journal:

Cancer Immunology, Immunotherapy

Year:

2009

Language:

english

File:

PDF, 787 KB

english, 2009

25

Heat shock protein peptides reactive in patients with Behçet's disease are uveitogenic in Lewis rats

M. R. STANFORD, E. KASP, R. WHISTON, A. HASAN, S. TODRYK, T. SHINNICK, Y. MIZUSHIMA, DC. DUMONDE, R. VAN DER ZEE, T. LEHNER

Journal:

Clinical & Experimental Immunology

Year:

1994

Language:

english

File:

PDF, 2.65 MB

english, 1994

26

Building better T-cell-inducing malaria vaccines

Stephen M. Todryk, Michael Walther

Journal:

Year:

2005

Language:

english

File:

PDF, 157 KB

english, 2005

27

Viral vector vaccines make memory T cells against malaria

Arturo Reyes-Sandoval, John T. Harty, Stephen M. Todryk

Journal:

Year:

2007

Language:

english

File:

PDF, 560 KB

english, 2007

28

The relationship between human effector and memory T cells measured by ex vivo and cultured ELISPOT following recent and distal priming

Stephen M. Todryk, Ansar A. Pathan, Sheila Keating, David W. Porter, Tamara Berthoud, Fiona Thompson, Paul Klenerman, Adrian V. S. Hill

Journal:

Year:

2009

Language:

english

File:

PDF, 450 KB

english, 2009

29

10.1038/5213

Kelly, Charles G., Younson, Justine S., Hikmat, Ban Y., Todryk, Stephen M., Czisch, Michael, Haris, Parvez I., Flindall, Ian R., Newby, Craig, Mallet, Anthony I., Ma, Julian K-C., Lehner, Thomas

Journal:

Nature Biotechnology

Year:

1999

Language:

english

File:

PDF, 157 KB

english, 1999

30

Tumor immunogenicity is determined by the mechanism of cell death via induction of heat shock protein expression

Melcher, Alan, Todryk, Stephen, Hardwick, Nicola, Ford, Martin, Jacobson, Michael, Vile, Richard G.

Journal:

Nature Medicine

Year:

1998

File:

PDF, 1.02 MB

1998

31

Malaria vaccines: the stage we are at

Todryk, Stephen M., Hill, Adrian V. S.

Journal:

Nature Reviews Microbiology

Year:

2007

Language:

english

File:

PDF, 360 KB

english, 2007

32

Malaria vaccines: the stage we are at

Todryk, Stephen M., Hill, Adrian V. S.

Journal:

Nature Reviews Microbiology

Year:

2011

File:

PDF, 38 KB

2011

33

Antitumor immune responses mediated by adenoviral GDEPT using nitroreductase/CB1954 is enhanced by high-level coexpression of heat shock protein 70

Djeha, Hakim A, Todryk, Stephen M, Pelech, Steven, Wrighton, Christopher J, Irvine, Alistair S, Mountain, Andrew, Lipinski, Kai S

Journal:

Cancer Gene Therapy

Year:

2005

Language:

english

File:

PDF, 312 KB

english, 2005

34

Tumour cell expression of B7 costimulatory molecules and interleukin-12 or granulocyte–macrophage colony-stimulating factor induces a local antitumour response and may generate systemic protective immunity

Chong, H, Todryk, S, Hutchinson, G, Hart, I R, Vile, R G

Journal:

Year:

1998

Language:

english

File:

PDF, 146 KB

english, 1998

35

Rapid adenoviral transduction of freshly resected tumour explants with therapeutically useful genes provides a rationale for genetic immunotherapy for colorectal cancer

Diaz, R M, Todryk, S, Chong, H, Hart, I R, Sikora, K, Dorudi, S, Vile, R G

Journal:

Year:

1998

Language:

english

File:

PDF, 310 KB

english, 1998

36

Genetic prodrug activation therapy (GPAT) in two rat prostate models generates an immune bystander effect and can be monitored by magnetic resonance techniques

Eaton, J D, Perry, M J A, Todryk, S M, Mazucco, R A, Kirby, R S, Griffiths, J R, Dalgleish, A G

Journal:

Year:

2001

Language:

english

File:

PDF, 3.56 MB

english, 2001

37

Suicide gene therapy in the rat model of prostate cancer

Perry, M, Todryk, S, Kirby, R, Dalgleish, A

Journal:

Prostate Cancer and Prostatic Diseases

Year:

1999

Language:

english

File:

PDF, 34 KB

english, 1999

38

The immunotherapy of prostate cancer

Dalgleish, A G, Perry, M J A, Eaton, J D, Hrouda, D, Todryk, S M, Kirby, R S

Journal:

Prostate Cancer and Prostatic Diseases

Year:

2000

Language:

english

File:

PDF, 96 KB

english, 2000

39

Coxsackie B and adenovirus receptor, integrin and major histocompatibility complex class I expression in human prostate cancer cell lines: implications for gene therapy strategies

Pandha, H S, Stockwin, L H, Eaton, J, Clarke, I A, Dalgleish, A G, Todryk, S M, Blair, G E

Journal:

Prostate Cancer and Prostatic Diseases

Year:

2003

Language:

english

File:

PDF, 97 KB

english, 2003

40

Coxsackie B and adenovirus receptor, integrin and major histocompatibility complex class 1 expression in human prostate cancer cell lines: implications for gene therapy strategies

Pandha, H S, Stockwin, L H, Eaton, J, Clarke, I A, Dalgleishm, A G, Todryk, S M, Blair, G E

Journal:

Prostate Cancer and Prostatic Diseases

Year:

2003

Language:

english

File:

PDF, 37 KB

english, 2003

41

Allogeneic whole-tumour cell vaccination in the rat model of prostate cancer

D. Hrouda, S.M. Todryk, M.J.A. Perry, B.E. Souberbielle, J. Kayaga, R.S. Kirby, A.G. Dalgleish

Journal:

BJU International

Year:

2000

Language:

english

File:

PDF, 119 KB

english, 2000

42

MIG (CXCL9) is a more sensitive measure than IFN-γ of vaccine induced T-cell responses in volunteers receiving investigated malaria vaccines

Tamara K. Berthoud, Susanna J. Dunachie, Stephen Todryk, Adrian V.S. Hill, Helen A. Fletcher

Journal:

Journal of Immunological Methods

Year:

2009

Language:

english

File:

PDF, 767 KB

english, 2009

43

Corrigendum to “MIG (CXCL9) is a more sensitive measure than IFN-γ of vaccine induced T-cell responses in volunteers receiving investigated malaria vaccines” [J. Immunol. Methods 340 (2009) 33–41]

Tamara K. Berthoud, Susanna J. Dunachie, Stephen Todryk, Adrian V.S. Hill, Helen A. Fletcher

Journal:

Journal of Immunological Methods

Year:

2011

Language:

english

File:

PDF, 93 KB

english, 2011

44

A natural immunization process prevents malaria

Stephen M. Todryk

Journal:

Trends in Parasitology

Year:

2010

Language:

english

File:

PDF, 199 KB

english, 2010

45

CD40 ligation for immunotherapy of solid tumours

Stephen M. Todryk, Alison L. Tutt, Michael H.A. Green, J.A. Smallwood, Nicole Halanek, Angus G. Dalgleish, Martin J. Glennie

Journal:

Journal of Immunological Methods

Year:

2001

Language:

english

File:

PDF, 238 KB

english, 2001

46

Immunogenicity of the candidate malaria vaccines FP9 and modified vaccinia virus Ankara encoding the pre-erythrocytic antigen ME–TRAP in 1–6 year old children in a malaria endemic area

Philip Bejon, Jedidah Mwacharo, Oscar K. Kai, Stephen Todryk, Sheila Keating, Trudie Lang, Sarah C. Gilbert, Norbert Peshu, Kevin Marsh, Adrian V.S. Hill

Journal:

Year:

2006

Language:

english

File:

PDF, 230 KB

english, 2006

47

Safety and immunogenicity of the malaria candidate vaccines FP9 CS and MVA CS in adult Gambian men

E.B. Imoukhuede, T. Berthoud, P. Milligan, K. Bojang, J. Ismaili, S. Keating, D. Nwakanma, S. Keita, F. Njie, M. Sowe, S. Todryk, S.M. Laidlaw, M.A. Skinner, T. Lang, S. Gilbert, B.M. Greenwood, A.V.S

Journal:

Year:

2006

Language:

english

File:

PDF, 336 KB

english, 2006

48

Cytoplasmic delivery of antigens, by Bacillus subtilis enhances Th1 responses

Jen-Min Huang, Roberto M. La Ragione, William A. Cooley, Stephen Todryk, Simon M. Cutting

Journal:

Year:

2008

Language:

english

File:

PDF, 1.13 MB

english, 2008

49

Comparing human T cell and NK cell responses in viral-based malaria vaccine trials

Tamara K. Berthoud, Helen Fletcher, David Porter, Fiona Thompson, Adrian V.S. Hill, Stephen M. Todryk

Journal:

Year:

2009

Language:

english

File:

PDF, 964 KB

english, 2009

50

Effect of route of immunisation and adjuvant on T and B cell epitope recognition within a streptococcal antigen

S.M. Todryk, C.G. Kelly, T. Lehner

Journal:

Year:

1998

Language:

english

File:

PDF, 919 KB

english, 1998